Virus Andes: del aislamiento geográfico sudamericano a la preocupación epidemiológica internacional
DOI:
https://doi.org/10.16921/pfr.v10i3.400Palabras clave:
Orthohantavirus, Virus Andes (ANDV), Hantaviridae, virus ARN segmentado, Síndrome Cardiopulmonar por Hantavirus (SCPH)Resumen
El presente texto aborda la evolución epidemiológica del Andes orthohantavirus (ANDV), un hantavirus del Nuevo Mundo que ha transitado de ser considerado una zoonosis rural regional en Argentina y Chile a convertirse en un foco de preocupación internacional tras las alertas sanitarias de 2026. A diferencia de los hantavirus del Viejo Mundo (asociados a fiebre hemorrágica con síndrome renal), el ANDV produce el Síndrome Cardiopulmonar por Hantavirus (SCPH), una patología de elevada letalidad caracterizada por edema pulmonar no cardiogénico y shock circulatorio fulminante.
Descargas
Citas
Belmar-Lucero, S., et al. (2021). Rodent ecology and hantavirus transmission in Chile. Pathogens.
Castillo, C., et al. (2023). Laboratory abnormalities in hantavirus cardiopulmonary syndrome. Revista Médica de Chile.
Coelho, R., et al. (2024). Virological characterization of a new isolated strain of Andes virus. PLOS Neglected Tropical Diseases.
El País. (2026). Un primer análisis genético del hantavirus del crucero confirma que es de la variante Andes y descarta mutaciones. El País.
Figueroa, R., et al. (2024). Cytokine profile in severe Andes virus infection. Frontiers in Cellular and Infection Microbiology.
Lobos, A., et al. (2024). ECMO support in severe Andes virus infection. Critical Care Medicine.
Martínez, V. P., et al. (2021). Super-spreader events in Andes virus outbreaks. Emerging Infectious Diseases.
Martínez-Valdebenito, C., et al. (2024). Viral shedding and viraemia of Andes virus during acute hantavirus infection. The Lancet Infectious Diseases.
Mertz, G. J., et al. (2021). Hantavirus cardiopulmonary syndrome in South America. New England Journal of Medicine.
Murgas, I., et al. (2021). Climate variability and hantavirus incidence in Chile. International Journal of Environmental Research and Public Health.
Padula, P. J., et al. (2022). Human transmission of Andes virus: Current evidence and controversies. Viruses.
Padula, P. J., et al. (2025). Thirty years of Andes virus research in South America. Lancet Regional Health Americas.
Riquelme, R., et al. (2023). Radiological findings in Andes hantavirus pulmonary syndrome. Radiología Chilena.
Rivera, P., et al. (2023). Diagnostic challenges in hantavirus pulmonary syndrome. BMJ Case Reports.
Toro, J., et al. (2024). Nosocomial risk of Andes hantavirus transmission. American Journal of Infection Control.
Torres-Pérez, F., et al. (2022). One Health approach to hantavirus surveillance in the Andes region. One Health.
Valdivieso, F., et al. (2022). Clinical predictors of mortality in Andes hantavirus pulmonary syndrome. Revista Chilena de Infectología.
Vial, P., et al. (2020). Management of severe hantavirus cardiopulmonary syndrome. Intensive Care Medicine.
Vial, P., et al. (2021). Andes virus infection in Chilean adults. Clinical Infectious Diseases.
World Health Organization. (2026). Hantavirus cluster linked to cruise ship travel, multi-country outbreak alert. World Health Organization.
