Pre-implantation genetic diagnostic procedures: from scientific and technical advances to bioethical implications
Abstract
Trying to determine if the human embryo is a person, is one of the questions to which philosophical, bioethical and biological aspects will come together, the same ones that necessarily disagree from their particular point of view; For this reason, a brief review of the various approaches is carried out applying the principles of philosophical anthropology and metaphysics at all stages of human life. From these principles it is proposed to build or build a bioethics that is objective, and that solves the cases and actions that have to do with human life and its nature.
On this issue there is a first emotional posture that makes us all be in favor of life and in defense of embryos, but to build an ethical system we cannot rely on mere feeling but raise it to the reflexive category and share the prescription of Diego Gracia, who points out that the feeling without reflection is blind and that the reflection without feeling is born dead, so when there are morals based on a system of strongly emotional values, it must be subjected to the control of reason, considering the means and ends . This is what is called the ethics of responsibility that must prevail at the dawn, of the solstice and the decline of life.
Post-genomic modernity opens the door to wonderful promises about the real possibility of manipulating in the diagnostic and even therapeutic perspective the rudimentary "human being" in the process of formation. From 1953 to today there have been spectacular scientific and technological conquests around the structure and function of DNA (genomic sciences): Non-invasive prenatal screening (NIPT), CRISPER / Cas9 (Lejeune, 1993)
Downloads
References
2. Lejeune J.¿Qué es el embrión humano? Madrid: Editorial Rialp; 1993.
3. Doudna J. A., & Charpentier, E. The new frontier of genome engineering with CRISPR-Cas9. Science , 346 (6213), 1258096-1; 2014.
4. García - Banderas A. & Estévez M. E. Bioética Clínica. Quito: Imprenta Terán; 2010.
5. Gracia D. Ética de los confines de la vida (III). Santa Fe de Bogotá: El Búho; 1998.
6. Zubiri J. Sobre el hombre; 1986.
7. García – Banderas A. & Estévez M., E.¿Es persona Humana el Embrión? Revista Iberoamericana de Educación Médica Contínua , 31-34; 2004.
8. Clavel J. ; 1998.
9. Baladeras M. Bioética. Madrid: Editorial Síntesis;1999.
10. (Clavel, 2007). Clavel, J. M. Biotecnología y principio de vida. Manejo de la vida reciente. Éxodo (90); 2007. 12-21.
11. Montgomery J. Non-invasive prenatal testing: ethical issues. Nuffield Council on Bioethics. London: Nuffield Council on Bioethics; 2017.
12. (Doudna & Charpentier, 2014).
13. Reardon S. Genetic details of controversial "three-parent baby" revealed. Nature (544); 2017. 17-18.
14. Zhang JE. Live birth derived from oocyte spindle transfer to prevent mitochondrial disease. Reprod. Biomed. Online (34); 2017. 361-368.
15. Wallace DC. & Chalkia D. Mittochondrial DNA Genetics and the Heteroplasmy Conundrum in Evolution and Disease; 2013. 1-25.
Copyright (c) 2019 Rural Family Practice

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.